Table II.

Preparation of PDMS/IMC Nanoparticles: Experimental Details and DLS Results

NP code	Blend code	Cross-linking reagents	Surfactant	Nanoparticle yield, %a	Drug load, %b	Z ave (nm)	PDI
A	1	–	S1	100	19.9 ± 0.1	252	0.413
B	1	TEOS, DBTDL	S1	93	17.5 ± 0.3	214	0.432
C	3	TEOS	S1	88	45.2 ± 0.3	246	0.422
D	4	TEOS, DBTDL	S1	81	55.6 ± 0.2	165	0.240
E	1	–	S2	100	20 ± 0.1	298	0,443
F	2	–	S2	89	39.7 ± 0.2	485	0.534
G	2	TEOS, DBTDL	S2	51	36.3 ± 0.3	452	0.256
H	3	–	S2	64	48.5 ± 0.2	488	0.470

^aCalculated as [(m ₀ − m _p)/m ₀] × 100

^bCalculated as [m _d/(m ₀ − m _p)] × 100

where: m ₀ initial mass of the blend; m _p mass of precipitate; m _d mass of encapsulated drug