. 2013 Aug 9;14(3):1227–1235. doi: 10.1208/s12249-013-0012-8

Table III.

Linearization of Release Data from Casein–Pectin Microparticles

Microparticle formulation	Higuchi model		First-order kinetics
Microparticle formulation	CD	K	CD	K
IND non-cross-linked spray dried	0.8787^a	4.86^a	0.7077^a	0.8790^a
IND non-cross-linked spray dried	0.8988^b	7.71^b	n.a.^b	n.a.^b
IND cross-linked spray dried	0.9806	5.65	0.8480	n.a.
IND non-cross-linked spouted bed dried	0.8482	19.62	0.8122	n.a.
IND cross-linked spouted bed dried	0.9429	5.98	0.7979	n.a.

I ND indomethacin, n.a. not assessed, K rate constant, CD correlation coefficient

^aFirst release phase

^bSecond release phase