Table 3.

Whole-brain activations linked to retrieval focus and valence of memories.

Brain regions	BA	Side	Talairach coordinates			T score	Cluster size
			x	y	z
A. DIRECT CONTRASTS
Emotion Positive vs. Context Positive
Inferior frontal gyrus	47	R	28	35	−5	6.08	54
Anterior cingulate	10	R	20	47	1	5.37
Middle temporal gyrus	21	L	−56	0	−7	5.63	26
Superior temporal gyrus	38	L	−56	11	−7	4.83
Precuneus	7	L	−4	−59	62	4.97	10
Inferior frontal gyrus	44	L	−55	12	10	4.91	10
Inferior frontal gyrus	47	L	−36	19	−8	4.85	41
Emotion Positive vs. Emotion Negative
Precentral gyrus	4	L	−44	−18	34	4.68	11
Context Negative vs. Context Positive
Inferior frontal gyrus	47	L	−36	19	−14	4.84	13
Hippocampus		L	−32	−12	−9	4.40	5
Hippocampus		R	32	−12	−13	4.47	5
B. INTERACTIONS
(Emotion Positive vs. Context Positive) vs. (Emotion Negative vs. Context Negative)
Middle temporal gyrus	21	L	−60	−4	−3	6.20	13
Hippocampus		L	−32	−16	−16	5.06	17
Caudate (tail)		L	−24	−42	13	4.98	24
Postcentral gyrus	3	L	−48	−18	34	4.51	28
Middle frontal gyrus	10	R	44	42	−5	4.40	14
(Context Negative vs. Emotion Negative) vs. (Context Positive vs. Emotion Positive)
Caudate (tail)		L	−24	−42	13	4.98	13
Hippocampus		L	−36	−16	−16	3.60	7
(Emotion Positive vs. Emotion Negative) vs. (Context Positive vs. Context Negative):
Hippocampus		L	−32	−16	−16	5.06	10
Cingulate gyrus	31	L	−24	−46	13	4.64	17
Postcentral gyrus	3	L	−48	−18	34	4.51	28
(Context Negative vs. Context Positive) vs. (Emotion Negative vs. Emotion Positive):
Hippocampus		L	−32	−16	−16	5.06	19
Caudate (tail)		L	−24	−42	13	4.98	13
Postcentral gyrus	3	L	−48	−18	34	4.51	15
Middle frontal gyrus	10	R	40	42	−5	4.32	11

Significant activations resulting from whole-brain analyses investigating direct contrasts and interactions are reported. For direct contrasts, a threshold of p < 0.001 was used, and for interactions a threshold of p < 0.005 was used. For the interaction analyses, the interaction contrast was inclusively masked with the corresponding direct contrast set up at p < 0.05. A cluster size of 10 contiguous voxels was used in all analyses, except for the MTL, where a cluster size of 5 contiguous voxels was used. BA = Brodmann’s area; L = left, R = right.