Table 4.
Deposition of PrPSc in microdissected areas of ME7 scrapie model
| DPI | A | B | C | D | E | F | G | ||||||||
| W | I | W | I | W | I | W | I | W | I | W | I | W | I | ||
| 30 | |||||||||||||||
| 60 | + | + | + | + | + | ||||||||||
| 90 | ? | + | + | + | + | ? | + | + | + | + | + | ||||
| 120 | + | N/A | ? | + | + | + | + | + | + | + | + | + | + | + | |
| 150 | + | N/A | + | + | + | + | + | + | + | + | + | + | + | + | |
| EP | + | N/A | + | + | + | + | + | + | + | + | + | + | + | + | |
Comparison of dissected brain areas (A-G as in Fig. 2) throughout time course of disease (dpi) in ME7 scrapie model. PrPSc deposition (+) visualized by immunocytochemistry (I) and western blotting (W)using 6H4Mab, (?) denotes where PrPSc was visualized in one brain only(see section 2.4), (N/A) section not available.