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. Author manuscript; available in PMC: 2014 Jul 2.
Published in final edited form as: Cell Metab. 2013 Jul 2;18(1):1–2. doi: 10.1016/j.cmet.2013.06.007

Figure.

Figure

ROS and stem cell self-renewal. Genetic and pharmacological interventions can raise or lower ROS levels in stem cells. Previous studies have established that increasing ROS levels within stem cells impairs self-renewal capacity. A new report suggests that lowering ROS levels can also be detrimental.