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Comparison of ketamine PBPK model arterial (red) and antecubital vein (blue) concentrations with the experimental data (squares) of Persson et. al. [12] (top panel). The bottom panel compares the model antecubital vein/arterial concentration ratio (black line) versus the experimental values (squares). Using a fractional contribution of muscle to antecubital vein blood of 0.05.
