Icam1tm1Bay T cells proliferate comparably compared to wild type T cells. Encephalitogenic T cells enriched by nylon-wool adherence from the spleens of wild type, Icam1tm1Bay mice and Icam1tm1Jcgr mice (n=4, all groups) undergoing active EAE, or T cells from healthy controls (naïve cells), were co-cultured with irradiated splenic APCs plus MOG peptide (0.125 - 4 μg/ml). The cells were pulsed with 3H-thymidine and harvested at 18 h for determination of radioisotope incorporation. The results shown are expressed as the mean + SEM of fold-induction of wild type, Icam1tm1Bay and Icam1tm1Jcgr T cell proliferation relative to background proliferation.