Skip to main content
. Author manuscript; available in PMC: 2013 Aug 28.
Published in final edited form as: Mol Immunol. 2010 Apr 3;47(9):1692–1700. doi: 10.1016/j.molimm.2010.03.005

Fig. 7.

Fig. 7

Splenic Icam1tm1Bay T cells produce elevated levels of IFN-γ compared to wild type and Icam1tm1Jcgr mice during EAE. Encephalitogenic T cells enriched by nylon-wool adherence from the spleens of wild type, Icam1tm1Bay and Icam1tm1Jcgr mice (n=4 all groups) undergoing active EAE (day 15), were co-cultured with irradiated splenic APCs from naïve donors and stimulated with MOG peptide (1μg/well). Supernatants were collected 48 hours after stimulation and assayed by ELISA to quantitate production of each cytokine. Cytokine production is shown as percent of wild type cytokine production.