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. Author manuscript; available in PMC: 2013 Aug 28.
Published in final edited form as: Mol Immunol. 2010 Apr 3;47(9):1692–1700. doi: 10.1016/j.molimm.2010.03.005

Table I.

EAE signs in wild-type mice, Icam1tm1Bay and Icam1tm1Jcgr mice.

CDIA Disease
OnsetB 		Disease
IncidenceC 		Mortality
Wild type (n=12) 58.3 16.3d 100 33%
Icam1tm1Jcgr (n=19) 31 17.3d 95 16%
Wild type (n=10) 56.4 13.4d 100 20%
Icam1tm1Bay (n=16) 64 13.7d 100 44%
A

Cumulative Disease Index is the mean of the sum of daily clinical scores observed between days 7 and 30.

B

Disease onset is defined as the first day of two consecutive days with a clinical score of two or more.

C

Disease incidence is defined as the percent of mice that displayed any clinical signs of disease.