Table 1.
Distribution of MTHFR C677T (genotype and allele) frequencies in unrelated migraine and control groups.
| Genotypes | Alleles | |||||
| Group | C/C | C/T | T/T | N (genotypes) | C | T |
| MO+MA | 104 (39%) | 125 (46%) | 39 (15%) | 268 | 333 (62%) | 203 (38%) |
| MA* | 64 (38%) | 72 (43%) | 32 (19%) | 168 | 200 (60%) | 136 (40%) |
| MO | 40 (40%) | 53 (53%) | 7 (7%) | 100 | 133 (66%) | 67 (34%) |
| Control | 117 (43%) | 129 (48%) | 23 (9%) | 269 | 363 (67%) | 175 (33%) |
*genotype distribution comparison (Trend χ2 = 5.72, P = 0.017), T/T genotype vs. C/C (OR = 2.54, 95% CI: 1.37 – 4.71).