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Tracings from a representative vascular responder depicting effects of MnPO microinjection of saline (A) or losartan (B) on arterial pressure (mmHg) and CO (kHz shift) changes following cocaine administration. Cocaine was administered (5 mg/kg iv) at the time point indicated by the arrow; microinjection of saline or losartan occurred 10 min prior to cocaine injection. Time scale (10 s) is indicated by bar.
