Table 3.

Effects of drug treatment alone immediately before cold stress

Stimulus	Class	No.	Mean AP, mmHg	Δ MAP, mmHg	HR, beats/min	Δ HR, beats/min	CO, kHz	Δ CO, kHz	Δ SVR, %	Δ SV, %
Muscimol	MR	6	115±6	0.17±3.2	423±15	−4±7	−3.0±0.2	−1.4±5.4	3.5±6.0	−4.3±6.0
	VR	9	119±5	1.04±1.0	405±11	1±4	−3.0±0.1	−3.0±1.2	4.1±1.7	−3.3±1.4
Losartan	MR	5	117±4	−2.2±1.4	403±25	10±11	−2.7±0.2	5.3±5.6	−6.0±4.7	2.9±6.3
	VR	7	119±6	0.24±1.2	404±24	2±8	−2.9±0.2	1.2±2.2*	−0.5±2.3*	0.97±3.1*

Values are means ± SE. No. is number of rats studied.

^*Significant change with treatment alone (P < 0.05); #significant difference between vascular and mixed responders (P < 0.05).