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Age-related deficits in cerebellar cortical Purkinje neurons. Total estimated number of Purkinje neurons in mice aged 4–25 months is shown. Significant loss of neurons was found in mice aged 12, 18, and 25 months. Values are mean ± SE. *p < .05 compared to 4 mo, ** p < .01 compared to 4 mo, ^ p < .05 compared to 8 mo.
