Figure 6.
MWM acquisition across the life span: Latency. Latency to escape the MWM in mice aged 4–25 months is shown. Learning is expressed by all groups, as latency decreases across Training Sessions. Overall, mice aged 25 months took significantly longer to find the platform than did 8 month-old mice (p < .05). The Age x Training Session interaction revealed differences in performance between 25 month-old mice and younger mice at Training Sessions 1, 8 and 9. Values are mean ± SE. *p < .05 compared to 4 mo, ** p < .01 compared to 4 mo, ^ p < .05 compared to 8 mo, ^^ p < .01 compared to 8 mo, + p < .05 compared to 18 mo.