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. Author manuscript; available in PMC: 2013 Aug 28.
Published in final edited form as: J Am Stat Assoc. 2012 Jan 24;106(496):1345–1360. doi: 10.1198/jasa.2011.ap10599

Table 1.

Significant KEGG pathways at FDR 1% and FWER of 10% (p-value cutoff = 0.1/18= 0.0056 by Bonferroni correction), identified from a postmenopausal hormone therapy proteomic study of the Women Health Initiative. P-values were calculated based on 10,000 resamplings.

Pathway names # non-missing
protein		 P-value of
RHT		 P-value of
SAT		 P-value of
HT/GHT		 P-value of
TD 		P-value of
TBS 		% significant
proteins*
Complement and coagulation cascades 45 0 0 0 0.002 0 22.2
Cell communication 12 0 0.001 0 0 0 16.7
Extracellular matrix receptor interaction 12 0 0 0 0 0 16.7
Focal adhesion 15 0 0 0 0 0 20.0
TGF-beta signaling 7 0.005 0.003 0.057 0.072 0 0.0
*

% of proteins with significant nominal p-value at 0.10 FWER (protein p-value cutoff of 0.10/369).