TABLE 5.
Comorbidity profiles across probands
| Disorder | RAN % (n) | PAN % (n) | AN(B) % (n) | χ 2 | p-Value | Group Differences |
|---|---|---|---|---|---|---|
| Childhood ANXIETY DISORDERS | ||||||
| Overanxious | 34.6 (36) | 38.2 (26) | 27.3 (6) | 0.90 | ns | — |
| Separation anxiety | 5.8 (6) | 10.3 (7) | 0.0 (0) | — | — | — |
| Anxiety disorders | ||||||
| Agoraphobia | 2.9 (3) | 1.5 (1) | 4.4 (1) | — | — | — |
| GAD | 11.5 (12) | 20.6 (14) | 4.4 (1) | 4.79 | ns | — |
| OCD | 37.5 (39) | 55.9 (38) | 52.2 (12) | 6.05 | .049 | RAN>PAN |
| Panic | 9.6 (10) | 13.4 (9) | 17.4 (4) | 1.33 | ns | — |
| PTSD | 8.6 (9) | 20.9 (14) | 9.1 (2) | 5.74 | ns | — |
| Social phobia | 17.3 (18) | 27.9 (19) | 21.7 (5) | 2.75 | ns | — |
| Specific phobia | 10.5 (11) | 14.7 (10) | 4.4 (1) | 2.00 | ns | — |
| Mood disorders | ||||||
| MDD | 64.4 (67) | 83.6 (53) | 87.0 (20) | 10.1 | .007 | RAN>PAN, AN(B) |
| Depression NOS | 1.0 (1) | 0.0 (0) | 0.0 (0) | — | — | — |
| Dysthymia | 1.9 (2) | 11.8 (8) | 8.7 (2) | 7.1 | .029 | RAN>PAN |
| Cyclothymia | 0.0 (0) | 0.0 (0) | 0.0 (0) | — | — | — |
| Bipolar I | 1.0 (1) | 0 (0.0) | 4.4 (1) | — | — | — |
| Bipolar II | 1.0 (1) | 1.5 (1) | 0.0 (0) | — | — | — |
| Bipolar NOS | 1.0 (1) | 1.5 (1) | 0.0 (0) | — | — | — |
| Substance use disorders | ||||||
| Alcohol abuse/dependence | 14.4 (15) | 25.0 (17) | 43.5 (10) | 10.1 | .006 | RAN<AN(B) |
| Drug abuse/dependence | 9.6 (10) | 21.5 (14) | 26.1 (6) | 6.5 | .039 | RAN<PAN, AN(B) |
Notes: GAD, generalized anxiety disorder; OCD, obsessive-compulsive disorder; PTSD, posttraumatic stress disorder; MDD, major depressive disorder; NOS, not otherwise specified; RAN, anorexia nervosa, restricting type; PAN, anorexia nervosa, purging type; AN(B), anorexia nervosa, with binge eating.