Fig. 4.

Analysis of p7 sequences. (a) Phylogeny. p7 sequences from the 11 isolates in this study are marked (•). The insertion of isolate QC64 is indicated (○). Subtypes 1a, 1b, 1c, 2a, 2b, 2c, 2i, 2k, 3a, 3b, 3k, 4a, 4f, 5a, 6a, 6i and 7a were included as references. Bar, 0.1 nucleotide substitutions per site. (b) Multiple sequence alignment. The consensus sequence and distinct amino acids are shown in standard International Union of Pure and Applied Chemistry (IUPAC) codes. Dashes indicate gaps relative to the 2e_QC64 insertion sequence. The isolate names are listed to the right of the alignment and the QC64 insertion is indicated in grey.