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. 2013 Sep;6(5):298–310. doi: 10.1177/1756285613484079

Figure 2.

Figure 2.

Evolution of contrast uptake in a newly formed lesion. Serial contrast-enhanced T1-weighted images obtained 5, 10, 15, and 20 min after gadolinium injection. A nodular-enhanced lesion located in the splenium of the corpus callosum (upper row) increases in size over time (centrifugal pattern), while an initial ring-enhanced lesion (lower row) becomes nodular (centripetal pattern).