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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: J Trauma Acute Care Surg. 2013 Jul;75(1 0 1):S40–S47. doi: 10.1097/TA.0b013e31828fa43d

Table 4.

Factor levels by INR and PTT-based coagulopathy

INR-based PTT-based
Coagulopathic Non-
coagulopathic
P-value Coagulopathic Non-
coagulopathic
P-value
N=69 N=87 N=32 N=123


PT 18.5 (16.5–24.0) 14.9 (13.8–16.6) <0.001 21.0 (16.8–28.9) 15.6 (14.2–18.0) <0.001
PTT 32.6 (27.5–38.0) 26.9 (23.4–30.5) <0.001 38.2 (32.9–48.6) 27.2 (23.9–31.6) <0.001
Fibrinogen 279 ± 34 209 ± 11 <0.001 213 ± 18 271 ± 30 <0.001
Factor II 61.9 ± 24.0 74.5 ± 26.1 0.01 52.3 ± 26.0 72.9 ± 24.1 0.001
Factor V 35.1 ± 23.0 57.6 ± 30.4 <0.001 24.8 ± 20.0 54.2 ± 28.7 <0.001
Factor VII 74.0 ± 29.9 91.5 ± 37.6 0.01 67.7 ± 26.8 87.4 ± 36.0 0.01
Factor VIII 302.0 ± 237.4 405.6 ± 237.4 0.01 180.2 ± 143.7 407.2 ± 240.7 <0.001
Factor IX 108.4 ± 78.1 125.4 ± 102.2 0.27 91.9 ± 48.6 124.6 ± 99.1 0.02
Factor X 60.3 ± 25.0 72.5 ± 32.6 0.02 57.0 ± 27.6 69.2 ± 29.9 0.07
AT III 70.7 ± 24.8 80.6 ± 27.0 0.01 68.6 ± 25.5 78.4 ± 26.3 0.06
D-dimer 4.0 (1.4–20.0) 3.8 (0.0–14.8) 0.25 12.8 (4.0–20.0) 3.0 (0.0–15.5) 0.02
Protein C 71.3 ± 24.9 87.9 ± 32.2 <0.001 66.5 ± 28.6 84.3 ± 29.7 0.003
aPC 37.2 (13.5–64.6) 8.1 (1.1–16.5) <0.001 37.2 (17.5–64.6) 6.9 (1.9–12.8) 0.001