Table 1.
Features and optimal weights
| Feature | 1-bit | 2-bit | 3-bit | 4-bit | Feature | 1-bit | 2-bit | 3-bit | 4-bit |
|---|---|---|---|---|---|---|---|---|---|
| Perfusion | |||||||||
| CBV2 | 0 | 0 | 0 | 11 | |||||
| Spectral height | CBV4 | 0 | 0 | 5 | 0 | ||||
| CNI | 1 | 3 | 7 | 15 | Peak height2 | 0 | 0 | 0 | 4 |
| CrNI | 0 | 0 | 0 | 0 | Peak height4 | 0 | 0 | 0 | 0 |
| CCrI | 0 | 3 | 7 | 14 | Recirc.3 | 0 | 0 | 0 | 7 |
| Cho1 | 0 | 0 | 0 | 6 | Recirc.2 | 0 | 0 | 0 | 0 |
| Cr1 | 1 | 3 | 7 | 15 | Peak width3 | 0 | 0 | 6 | 11 |
| NAA1 | 0 | 0 | 2 | 2 | Peak width2 | 1 | 3 | 0 | 10 |
| Cho2 | 0 | 0 | 6 | 0 | Peak time3 | 0 | 0 | 0 | 5 |
| Cr2 | 0 | 0 | 4 | 0 | Peak time2 | 0 | 0 | 0 | 6 |
| NAA2 | 0 | 0 | 7 | 0 | % recovery3 | 0 | 0 | 0 | 0 |
| Lactate1 | 1 | 3 | 7 | 13 | % recovery2 | 0 | 3 | 7 | 13 |
| Lipid2 | 1 | 3 | 6 | 12 | |||||
| Cho3 | 1 | 3 | 0 | 10 | Spectral widths | ||||
| Cr3 | 0 | 2 | 0 | 0 | Cho linewidth | 0 | 0 | 0 | 0 |
| NAA3 | 1 | 3 | 3 | 15 | Cr linewidth | 0 | 0 | 2 | 0 |
| NAA linewidth | 0 | 0 | 0 | 0 | |||||
| Diffusion | Cho linewidth3 | 0 | 0 | 2 | 4 | ||||
| FA | 0 | 0 | 0 | 13 | Cr linewidth3 | 0 | 0 | 0 | 0 |
| ADC2 | 0 | 0 | 0 | 13 | NAA linewidth3 | 0 | 0 | 2 | 9 |
| ADC3 | 0 | 0 | 0 | 0 | Cho linewidth2 | 0 | 0 | 0 | 6 |
| Cr linewidth2 | 0 | 0 | 0 | 0 | |||||
| NAA linewidth2 | 0 | 3 | 6 | 13 |
1
Normalized within each patient to standard error of the noise
2
Normalized within each patient to the mean value in normal appearing white matter (NAWM)
3
Standardized to the mean and standard deviation in normal appearing white matter for each patient
4
Scaled linearly such that 0 is the estimated value of normal appearing white matter and 1 is normal appearing gray matter for each patient