Table 4.
Geometric Mean Values for Percentages of Calories Derived From Carbohydrate and Fat Measured 10 Years After Baseline, by FTO rs8050136 Genotype, Among Multiethnic Cohort Study Participants (1993–2006) With Available 10-Year Follow-up Diet Data (n = 10,766) and Those Who Remained Diabetes-Free (n = 5,350)
FTO rs8050136 Genotype |
P-trend | ||||||
---|---|---|---|---|---|---|---|
CC |
CA |
AA |
|||||
Geometric Mean |
SE | Geometric Mean |
SE | Geometric Mean |
SE | ||
% of calories from carbohydrate | |||||||
Model 1a | 50.43 | 0.12 | 49.91 | 0.13 | 50.10 | 0.27 | 0.02 |
Model 2b | 50.52 | 0.12 | 50.06 | 0.13 | 50.33 | 0.27 | 0.07 |
Model 3c | 50.47 | 0.13 | 50.00 | 0.14 | 50.29 | 0.27 | 0.07 |
Participants who were diabetes-free during the 10 years postbaselineb | 50.92 | 0.18 | 50.34 | 0.20 | 50.72 | 0.38 | 0.11 |
% of calories from fat | |||||||
Model 1 | 31.32 | 0.10 | 31.69 | 0.11 | 31.96 | 0.22 | 0.001 |
Model 2 | 31.21 | 0.10 | 31.49 | 0.11 | 31.67 | 0.21 | 0.01 |
Model 3 | 31.26 | 0.10 | 31.57 | 0.11 | 31.75 | 0.22 | 0.01 |
Participants who were diabetes-free during the 10 years postbaseline | 30.73 | 0.14 | 31.01 | 0.16 | 31.12 | 0.30 | 0.12 |
Abbreviation: SE, standard error.
a Results were adjusted for age at blood draw, sex, race/ethnicity, and follow-up time.
b Model 1 with additional adjustment for baseline body mass index.
c Model 1 with additional adjustment for body mass index at the time of diet measurement.