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. 2013 Aug;5(4):559–566. doi: 10.3978/j.issn.2072-1439.2013.07.35

Table 1. Functional properties of indacaterol against the three human β-adrenoceptor subtypes. From Battram et al. (7).

β1 pEC50 IA β2 pEC50 IA β3 pEC50 IA Selectivity for β2 over β1
6.60±0.24 16±2 8.06±0.02 73±1 6.72±0.13 113±7 1.46

pEC50 is the negative logarithm of the molar drug concentration that produces a cAMP response equal to 50% of its maximal response. IA is the percentage of isoprenaline-induced maximal response. Selectivity for β2 over β1 expressed as pEC50 at β2-adrenoceptor–pEC50 at β1-adrenoceptor.