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. 2013 Aug;5(4):549–558. doi: 10.3978/j.issn.2072-1439.2013.08.04

Figure 2.

Figure 2

Inspiratory capacity at Week 12: INSTRUST 1 and 2 studies. Differences between treatments (indacaterol plus tiotropiume-tiotropium plus placebo) in effect on inspiratory capacity (IC) at intervals post dose at week 12. Data are least squares mean ±95% confidence intervals. All differences are significant at *P<0.05, **P<0.01, ***P<0.001. [Reproduced from (Concurrent use of indacaterol plus tiotropium in patients with COPD provides superior bronchodilation compared with tiotropium alone: a randomised, double-blind comparison; Mahler DA, D’Urzo A, Bateman ED, Ozkan SA, White T, Peckitt C, Lassen C, Kramer B, 2012;67:781-8) with permission from BMJ Publishing Group Ltd] (55).