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. Author manuscript; available in PMC: 2014 May 17.
Published in final edited form as: Angew Chem Int Ed Engl. 2013 Apr 18;52(21):5490–5496. doi: 10.1002/anie.201301439

Scheme 1.

Scheme 1

illustration of the construction of fluorescent DNA nanodevices on target living cell surfaces based on an aptND platform, where A) three types of fluorescent DNA nanodevices, preformed via HCR-based self-assembly upon initiation by aptamer-tethered trigger probes, are anchored on target cell surfaces, or B) aptamer seed probes initiate in situ self-assembly of fluorescent DNA nanodevices on target cell surfaces by either I) cascading alternative hybridization of two partially complementary monomers or II) HCR.