Table 1.

Meta-analyses of significant associations between birth weight and components/correlates of metabolic syndrome

Study	N	Exposure	Birth Weight Reference Group	Outcome	Effect OR [95 % CI]
Silveira et al. 2008 [11]	5867	LBW (<2.5 kg)	>3.4 kg	Metabolic syndrome	2.53 [1.57, 4.08]
Harder et al. 2007 [12]	132,180	HBW (>4 kg)	2.5–4 kg	T2DM	1.36 [1.07, 1.73]
		LBW (<2.5 kg)	2.5–4 kg	T2DM	1.47 [1.26, 1.72]
Whincup et al. 2008 [13]	152,084	BW continuous	per 1–kg rise	T2DM	0.80 [0.72, 0.89]
Mu et al. 2012 [14]	39,641	LBW (<2.5 kg)	>2.5 kg	hypertension	1.21 [1.13, 1.30]
	32,951	HBW (>4 kg)	<4 kg	hypertension	0.78 [0.71, 0.86]
	32,351	LBW (<2.5 kg)	>2.5 kg	SBP	2.58 [1.51, 3.64]
	28,144	HBW (>4 kg)	<4 kg	SBP	−2.08 [−2.98, −1.17]
de Jong et al. 2012 [15]	3080	preterm or VLBW	term	SBP	2.50 [1.67, 3.32]
Gamborg et al. 2007 [16]	197,954	BW continuous	per 1–kg rise	SBP in females	−2.80 [−3.85, −1.76]
				SBP in males	−1.52 [−2.27, −0.77]
Zhao et al. 2012 [17]	211,457	HBW (>4 kg)	2.5–4 kg	BMI>25	1.46 [1.27, 1.68]
Yu et al. 2011 [18]	39,216	HBW (>4 kg)	<4 kg	BMI>30	2.07 [1.91, 2.24]
Owen et al. 2003 [19]	23,247	BW continuous	per 1–kg rise	Total cholesterol	−0.05 [−0.08, −0.02]

HBW high birth weight, LBW low birth weight, SBP systolic blood pressure, T2DM type 2 diabetes mellitus