Table 1. Baseline Characteristics.
| Sample for Baseline AoD Analyses | Sample for Change in AoD Analyses | |||||
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| Characteristic | Combined Sample | Original Cohort | Offspring Cohort | Combined Sample | Original Cohort | Offspring Cohort |
| Number of unique participants, n | 6,493 | 2,074 | 4,419 | 4,523 | 941 | 3,582 |
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| Number of observations, n | 13,605 | 3,005 | 10,600 | 7,098 | 941 | 6,157 |
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| Age, yrs | 56 ± 14 | 72 ± 7 | 51 ± 12 | 58 ± 12 | 75 ± 5 | 55 ± 10 |
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| Men | 46 | 40 | 48 | 47 | 39 | 48 |
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| Weight, kg | 74.8 ± 16.1 | 69.8 ± 13.9 | 76.2 ± 16.4 | 76.6 ± 16.5 | 69.7 ± 14.1 | 77.6 ± 16.6 |
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| Height, m | 166.8 ± 9.9 | 161.8 ± 9.7 | 168.2 ± 9.4 | 167.2 ± 9.7 | 161.5 ± 9.6 | 168.0 ± 9.4 |
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| Body mass index, kg/m2 | 26.7 ± 4.7 | 26.5 ± 4.3 | 26.8 ± 4.8 | 27.2 ± 4.9 | 26.6 ± 4.5 | 27.3 ± 4.9 |
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| Systolic blood pressure, mm Hg | 129 ± 20 | 142 ± 21 | 126 ± 18 | 130 ± 20 | 148 ± 22 | 128 ± 19 |
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| Diastolic blood pressure, mm Hg | 77 ± 10 | 77 ± 10 | 78 ± 10 | 77 ± 10 | 76 ± 11 | 77 ± 10 |
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| Hypertension | 41 | 68 | 33 | 44 | 78 | 39 |
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| Antihypertensive treatment | 24 | 43 | 18 | 27 | 54 | 23 |
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| Diabetes | 7 | 9 | 6 | 8 | 10 | 7 |
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| Smoking | 25 | 22 | 26 | 18 | 13 | 19 |
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| Baseline aortic root size, crude, mm | 32 ± 4 | 32 ± 4 | 31 ± 4 | 32 ± 4 | 33 ± 4 | 32 ± 4 |
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| Change in aortic root size over 8 yrs, mm | – | – | – | 1.1 ± 3.2 | 1.5 ± 3.3 | 1.1 ± 3.2 |
Values are mean ± SD or %, unless otherwise indicated.
AoD = aortic root diameter.