Table 2.
Conventional echocardiographic measures of patients with beta-thalassemia major (TM) and healthy controls
| Variables | Patients with TM ( n = 100) | Group 2 (Controls) ( n = 100) | P -value |
|---|---|---|---|
| LVEDD (mm) | 47.6±5.2 (39–59) | 45.5±5.4 (36–53) | <0.05 |
| LVESD (mm) | 28.1±5.2 (23–38) | 25.2±3.7 (19–30) | <0.05 |
| IVS (d) (mm) | 8.9±2.2 (7.7–13.1) | 8.4±1.7 (4.7–11.4) | Ns |
| IVS(s) (mm) | 12.1±3.2 (6.9–16) | 10.9±1.9 (8–12.9) | Ns |
| LVPWD (d) (mm) | 8.3±1.9 (7.8–12/1) | 7.9±2.3 (6.5–12.8) | Ns |
| LVPWD(s) (mm) | 11.3±3.1 (7.9–13.9) | 11.1±1.3 (9.8–12.9) | Ns |
| FS (%) | 40.6±6.1 (34–52) | 45.8±7.3 (40–58) | Ns |
| EF (%) | 54.8±9.3 (45–68) | 78.5±5.8 (69–81) | <0.05 |
| Mitral E (m/s) | 1.1±0.4 (0.83–1.5) | 1.01±0.21(0.9–1.6) | NS |
| Mitral A (m/s) | 0.8±0.5 (0.5–1.4) | 0.7±0.8 (0.5–0.8) | Ns |
| E/A ratio | 1.4±1.01 (0.9–1.8) | 1.8±0.8 (1.2–2.9) | <0.05 |
| DT (ms) | 128±27 (83–179) | 132±30 (91–180) | Ns |
NS, None Significant LVEDD, Left ventricular end-diastolic diameter LVESD Left ventricular end-systolic diameter IVS(s) Interventricular septum diameter in systole IVS (d) Interventricular septum diameter in diastole LVPWD(s) Left ventricular posterior wall diameter in systole LVPWD (d) Left ventricular posterior wall diameter in diastole FS Fractional shortening EF Ejection fraction Mitral E Peak early diastolic wave Mitral A Peak late diastolic wave DT E wave deceleration time