Table 3.
Comparison of Tissue Doppler imaging measurements in patients with beta-thalassemia major (TM) and healthy controls
| Variables | Group 1 (Patients with TM) ( n =100) | Group 2 (Controls) ( n =100) | P -value |
|---|---|---|---|
| Basal septal wal | |||
| Sm (cm/s) | 7.9±1.5 (5.8–11.4) | 8.9±1.7 (5.9–12.6) | NS |
| Em (cm/s) | 13.2±3.3 (9.8–18.1) | 14.2±3.3 (11.5–16.3) | NS |
| Am (cm/s) | 5.6±1.6 (3.8–10.7) | 7.9±1.8 (5.4–8.9) | <0.05* |
| Mid-septal wall | |||
| Sm (cm/s) | 6.1±1.3 (4.4–9.7) | 6.8±1.7 (4.8–9.3) | NS |
| Em (cm/s) | 9.9±1.6 (7.2–12.3) | 11.8±2.4 (7.9–14.9) | <0.05* |
| Am (cm/s) | 4.9±1.3 (3.4–9.1) | 5.4±1.9 (3.9–7.9) | <0.05* |
| Basal lateral LV wall | |||
| Sm (cm/s) | 10.8±2.8 (6.9–16.9) | 11.9±2.5 (8.3–15.9) | NS |
| Em (cm/s) | 16.9±3.06 (13.1–25.3) | 17.5±3.04 (12.1–22.9) | NS |
| Am (cm/s) | 6.7±1.7 (3.8–10.9) | 9.8±2.8 (7.1–11.7) | <0.05* |
| Mid-lateral LV wall | |||
| Sm (cm/s) | 9.7±2.8 (4.9–15.5) | 12.8±2.9 (7.9–14.9) | <0.05* |
| Em (cm/s) | 17.9±2.9 (11.3–21.7) | 19.7±3.8 (12.8–19.7) | NS |
| Am (cm/s) | 5.5±1.6 (3.2–17.8) | 5.9±1.9 (4.1–9.8) | <0.05* |
Data were expressed as mean ± SD
NS, None Significant LV, left ventricle Sm, peak myocardial systolic velocity Em, peak myocardial early diastolic velocity Am, peak myocardial late diastolic velocity