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. 2013 Sep 1;3(9):1573–1576. doi: 10.1534/g3.113.007591

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Copyright © 2013 Kugler et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution Unported License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Maternal loss of miR-969 and miR-9c leads to elevated primordial germs cell (PGC) number variance. (A) Average PGC number variance is elevated in embryos derived from miR-969 mutant mothers in comparison with control and rescued embryos. Genotypes are (a) Df(1)BSC352/miR-969^KI;;T-969@Fb/+, (b) Df(1)BSC352/miR-969^KI, and (c) Df(1)BSC352/+. (B) Average PGC number variance is elevated in embryos derived from miR-9c mutant mothers in comparison with control and rescued embryos: (d) miR-9c^KO/miR-9c^KO;T-9c@Fb/+, (e) miR-9c^KO/miR-9c^KO;+/nosGal4, (f) miR-9c^KO/miR-9c^KO;T-9c@Fb/nosGal4, (g) miR-9c^KO/+;T-9c@Fb/+, and (h) +/miR-9c^KO;+/nosGal4. (C) Increased PGC number variance (y-axis) does not generally increase with reduced PGC numbers (x-axis). Data points were originally published in Kugler et al. 2010.