Fig. 1.
Photographs of the Ednrb+/+ and Ednrb−/− mice. a Ednrb+/+ mouse and −/− littermate at 24 days of age. b Representative picture of entire gut showing megacolon and aganglionic segment of Ednrb−/− mouse compared to Ednrb+/+ mouse. Arrow marks the transition zone. c Representative picture showing markedly sizereduced spleen of Ednrb−/− mouse by comparing to Ednrb+/+ littermate