Table 1. Effects of 5-HT on pro-inflammatory cytokine production.
in vitro treatment | IL-1β | IL-6 | ||
WT | IL-13−/− | WT | IL-13−/− | |
Media | 15.53±3.13 | 12.95±1.59 | 6.88±0.67 | 4.67±1.96 |
5-HT | 22.07±1.48 | 15.26±4.33 | 12.42±0.93 | 11.83±1.16 |
Effects of 5-HT on IL-1β and IL-6 production by peritoneal macrophages isolated from WT and IL-13−/− following DSS administration. Data is expressed as percent increase with respect to their controls; mean ± SEM of 4 to 6 mice in each group done in triplicates.