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. 2013 Aug 28;8(8):e73423. doi: 10.1371/journal.pone.0073423

Figure 5. Human factor IX protein in HLGP after i.d. DNA (pNGVL3/CMVi/hFIXm1) injection and non-invasive GET.

Figure 5

A, Human factor IX in HLGP skin. Delivery groups, IO: 50 µL DNA without pulse delivery; GET: 50 µL DNA with 1 pulse delivery on the injection site. Bars represent mean ± SD. 3 sites were analyzed for each delivery. * p<0.05 by Student's t-test. B, Human factor IX in HLGP plasma. Delivery groups, IO: 50 µL DNA without pulse delivery; GET: 50 µL DNA with 1 pulse delivery on the injection site. 4GET: 4×50 µL DNA with 4 pulse delivery on the injection site. Bars represent mean ± SD. 4 HLGPs were analyzed for each delivery group.