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. 2013 Aug 28;8(8):e73502. doi: 10.1371/journal.pone.0073502

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© 2013 Becker et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Percentage changes in mPAP under (A) normal ventilation (3-min observation interval) and (B) the peak of hypoxia induced PAP increase (1-min observation interval) during univentilation cycles versus representative vehicle cycle for each group (mean ± SEM, N = 6). mPAP, mean pulmonary artery pressure; SEM, standard error of the mean. *p<0.05 in treatment group development over time as compared with vehicle.