Table 2. Genotype distributions of those SNPs significantly associated with hypertension.
SNP | Gene | Group | Genotype | MAF | P Value | OR | 95% CI | ||
rs3789678 | AGT | Case | 690 (CC) | 159 (CT) | 45 (TT) | 0.14 | 0.002 | 1.32 | 1.10–1.58 |
Control | 626 (CC) | 236 (CT) | 41 (TT) | 0.18 | |||||
rs2493132 | AGT | Case | 373 (CC) | 410 (CT) | 111 (TT) | 0.35 | 0.003 | 1.23 | 1.07–1.40 |
Control | 316 (CC) | 452 (CT) | 137 (TT) | 0.40 | |||||
rs4305 | ACE | Case | 155 (AA) | 441 (AG) | 300 (GG) | 0.36 | 0.001 | 1.26 | 1.10–1.44 |
Control | 103 (AA) | 450 (AG) | 348 (GG) | 0.42 | |||||
rs275645 | AGTR1 | Case | 455 (AA) | 395 (AG) | 43 (GG) | 0.27 | 0.002 | 1.27 | 1.09–1.48 |
Control | 535 (AA) | 333 (AG) | 37 (GG) | 0.22 | |||||
rs3802230 | CYP11B2 | Case | 80 (AA) | 348 (AC) | 470 (CC) | 0.28 | 0.001 | 1.28 | 1.13–1.48 |
Control | 89 (AA) | 428 (AC) | 385 (CC) | 0.34 | |||||
rs10086846 | CYP11B2 | Case | 469 (CC) | 277 (CT) | 151 (TT) | 0.32 | 0.006 | 1.21 | 1.06–1.39 |
Control | 413(CC) | 318 (CT) | 172 (TT) | 0.37 |
The P values were obtained from the comparison of two allele frequencies. OR, odds ratio; CI, confidence interval.