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. 2013 Aug 28;8(8):e72701. doi: 10.1371/journal.pone.0072701

Table 2. Genotype distributions of those SNPs significantly associated with hypertension.

SNP Gene Group Genotype MAF P Value OR 95% CI
rs3789678 AGT Case 690 (CC) 159 (CT) 45 (TT) 0.14 0.002 1.32 1.10–1.58
Control 626 (CC) 236 (CT) 41 (TT) 0.18
rs2493132 AGT Case 373 (CC) 410 (CT) 111 (TT) 0.35 0.003 1.23 1.07–1.40
Control 316 (CC) 452 (CT) 137 (TT) 0.40
rs4305 ACE Case 155 (AA) 441 (AG) 300 (GG) 0.36 0.001 1.26 1.10–1.44
Control 103 (AA) 450 (AG) 348 (GG) 0.42
rs275645 AGTR1 Case 455 (AA) 395 (AG) 43 (GG) 0.27 0.002 1.27 1.09–1.48
Control 535 (AA) 333 (AG) 37 (GG) 0.22
rs3802230 CYP11B2 Case 80 (AA) 348 (AC) 470 (CC) 0.28 0.001 1.28 1.13–1.48
Control 89 (AA) 428 (AC) 385 (CC) 0.34
rs10086846 CYP11B2 Case 469 (CC) 277 (CT) 151 (TT) 0.32 0.006 1.21 1.06–1.39
Control 413(CC) 318 (CT) 172 (TT) 0.37

The P values were obtained from the comparison of two allele frequencies. OR, odds ratio; CI, confidence interval.