Figure 2. Muscle fiber typing of wild-type and PTN-overexpressing mice after 14 days HU or 91 days space flight.
A) Representative soleus muscle sections immunostained by means of monoclonal antibodies specific for the different myosin heavy chain isoforms. B–C) Fiber type composition of Sol (B) and EDL (C) muscles determined as shown in A. Each bar is the mean ± SEM from 2-to-10 mice. Statistical analysis performed with unpaired Student’s t test indicates significant change (at least P<0.05) versus WT-G (*), WT-HU (§), PTN-G (#), and PTN-HU (°).