Figure 3. Muscle MyHC isoform composition of wild-type and PTN-overexpressing mice after 14 days HU or 91 days space flight.

A) MyHC isoforms were separated by SDS-PAGE and stained with Coomassie blue. Densitometric analysis on MyHC isoforms is reported for Sol (B) and EDL (C) muscles. Each bar is the mean ± SEM from 2-to-7 mice. Statistical analysis performed with unpaired Student’s t test indicates significant change (at least P<0.05) versus WT-G (*), WT-HU (§), PTN-G (#), PTN-HU (°).