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. 2013 Aug 28;8(8):e71215. doi: 10.1371/journal.pone.0071215

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© 2013 Li et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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A. Methylation patterns of DAZL in normozoospermia. B. Methylation patterns of DAZL in asthenozoospermia. C. Methylation patterns of DAZL in oligozoospermia. D. Percentages of clones with four different methylation categories of DAZL promoter. NZ, normozoospermia; AZ, asthenozoospermia; OZ, oligozoospermia; C, number of clones; P, patient codes with number of clones per methylation patterns. CpGs: methylated shown in black, unmethylated shown in white. White bars: complete unmethylation; grey bars: mild hypermethylation; black bars: moderate hypermethylation; dotted bars: severe hypermethylation. Data are means+SD (n = 20 patients from each group). Statistically significant differences from the control group (NZ) are represented with asterisks: *P<0.05, **P<0.01.