Table 2.

The association of diabetic status in ESRD patients with getting listed/transplanted in the entire study population by Cox models¹,²

	Outcome: listed/transplanted without being listed		Outcome: Transplant for those who got listed

	HAZARD RATIO (95% CI)		HAZARD RATIO (95% CI)
	MODEL 1	MODEL 2	MODEL 1	MODEL 2
Diabetes (compared to non- diabetes)	0.80(0.79–0.81)	1.07(1.05–1.09)	0.72(0.70–0.73)	1.01(0.99–1.03)^*

Age at ESRD onset	0.95(0.95–0.95)	0.98(0.98–0.98)	0.95(0.95–0.95)	0.98(0.98–0.98)

Sex
Male	Reference		Reference
Female	0.83(0.82–0.84)	0.83(0.82–0.84)	0.84(0.82–0.85)	0.84(0.83–0.86)

Race
White	Reference		Reference
Black	0.77(0.76–0.78)	0.75(0.74–0.76)	0.50(0.49–0.51)	0.50(0.49–0.51)
Native American	0.82(0.77–0.87)	0.81(0.77–0.86)	0.60(0.55–0.65)	0.59(0.54–0.64)
Asian	1.29(1.26–1.33)	1.21(1.18–1.24)	0.70(0.67–0.72)	0.63(0.61–0.66)
Other	0.68(0.65–0.72)	0.66(0.63–0.70)	0.46(0.42–0.49)	0.44(0.41–0.47)

Hemoglobin (g/dl)
≤ 10	Reference		Reference
> 10	1.15(1.14–1.17)	1.14(1.13–1.16)	1.30(1.28–1.32)	1.29(1.27–1.32)
Missing	1.02(1.00–1.04)^*	1.02(1.00–1.04)^*	1.17(1.14–1.21)	1.17(1.13–1.20)

Albumin (g/dl)
< 3.5	Reference		Reference
≥ 3.5	1.46(1.44–1.49)	1.41(1.38–1.43)	1.49(1.46–1.53)	1.44(1.41–1.47)
Missing	1.14(1.13–1.17)	1.11(1.09–1.13)	1.14(1.12–1.17)	1.11(1.09–1.14)

GFR (ml/min/ 1.73m²)
< 15	Reference		Reference
15 – 30	0.59(0.57–0.61)	0.62(0.61–0.64)	0.50(0.57–0.62)	0.62(0.60–0.65)
Missing	0.71(0.67–0.75)	0.73(0.70–0.77)	0.68(0.63–0.74)	0.71(0.65–0.76)

Duration of pre-ESRD nephrology care
No nephrology care	Reference		Reference
Less than 6 months	1.82(1.73–1.92)	1.83(1.74–1.92)	2.23(2.03–2.45)	2.22(2.02–2.44)
6 to 12 months	1.51(1.45–1.57)	1.52(1.46–1.58)	1.92(1.77–2.08)	1.93(1.78–2.08)
More than 12 months	1.91(1.83–1.99)	1.95(1.87–2.03)	2.96(2.75–3.19)	3.02(2.80–3.25)
Missing	1.35(1.31–1.40)	1.38(1.34–1.42)	2.03(1.91–2.16)	2.05(1.92–2.18)

Geographic location
Rural	Reference			Reference
Urban	0.99(0.97–1.01)^*	0.97(0.95–0.99)^*	0.86(0.84–0.88)	0.84(0.82–0.86)
Unknown	0.82(0.77–0.86)	0.81(0.76–0.85)	0.77(0.71–.0.83)	0.75(0.70–0.81)

Median income (US $ per annum)	1.00(1.00–1.00)	1.00(1.00–1.00)	1.00(1.00–1.00)	1.00(1.00–1.00)

Body mass index (kg/m²)	-	1.00(0.99–1.00)	-	0.98(0.98–0.99)

Comorbidity index	-	0.73(0.73–0.74)	-	0.72(0.71–0.73)

Cox model 1 was adjusted for age at ESRD onset, sex, race, history of diabetes, hemoglobin, GFR, Serum albumin, geographic location, median income, and duration of pre-ESRD nephrology care.

Cox model 2 was adjusted for BMI and Comorbidity index in addition to the covariates listed above in model 1.

Note: P value was <0.001 for all the above variables in both the models except i) for diabetes variable for the outcome transplant for those who got listed in the 2nd model (P=0.42), ii) missing category in hemoglobin for the outcome listed/ transplanted without being listed (P=0.12 and 0.18 for model 1 and 2 respectively), and iii) for urban category in geography for the outcome listed/ transplanted without being listed (P=0.22 and 0.002 for model 1 & 2 respectively)