Figure 1.
Electroretinograms from normal (left column) and putative mutant (right column) mice in response to flash stimuli against a dark background (A and B) or against a steady adapting background (3cd/m2, C). Stimuli are indicated by numbers near each response. (A) The STR (scotopic threshold response) is found in every normal, fully dark-adapted mouse but was not found in 4 putative mutants. (B) Putative mutants were found with either inverted b-wave or slowed a-wave and absent b-wave (upper traces), inverted c-wave (middle traces) or attenuated b-wave (lower traces). (C) Cone responses are evoked in the presence of a steady adapting light (3cd/m2) but in one putative mutant mouse the cone response was inverted in sign. Illumination of the various stimuli were: 1, 0.00017cds/m2; 2, 0.00028cds/m2; 3, 0.00066cds/m2; 4, 0.0083cds/m2; 5, 0.158cds/m2;6, 0.331cds/m2; 7, 0.637cds/m2; 8, 1.19cds/m2; 9, 27.88cds/m2.