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. Author manuscript; available in PMC: 2014 Aug 1.
Published in final edited form as: Biomaterials. 2013 May 28;34(26):6185–6193. doi: 10.1016/j.biomaterials.2013.04.063

Fig. 7. Improved efficiency in delivering of liposomal FTY720 with dILs and enhanced cytotoxicity on B-CLL cells.

Fig. 7

B-CLL cells were incubated with indicated formulations of IL or dIL FTY720 at 4 μM of FTY720 and 0.1 μg/ml mAbs in total for 24 hr. The viability of the cells were then assessed by annexin V/PI analysis by flow cytometry (mean ± SD). Encapsulating FTY720 into liposomes and targeting it with mAbs can induce potent target cell apoptosis compared to the corresponding IL or dIL groups without FTY720 is shown (n= 6, p-value<0.0001).