Figure 1.

Method flowchart. (A) Adverse event descriptions were extracted from the summaries of product characteristics (SPCs), representing the baseline dictionary. (B) The lexemes in the baseline dictionary were assigned into seven dictionary groups, split in two groups according to whether they are involved in post-coordination or not. The first number below each group indicates the number of concepts and the second number the unique identifiers in the group. (C) Tagging using the baseline dictionary. (D) Tagging using the group dictionary and subsequent post-coordination of tagged lexemes. (E) The four filtering groups split according to whether they disqualify sentence subparts or the whole sentence in the filtering step. The number below each group indicates the number of concepts. (F) Filtering, where any disqualified possible ADE is removed. (G) The final output of the pipeline.