. 2013 Aug 13;3(8):e290. doi: 10.1038/tp.2013.63

Table 2. Top genetic variants associated with cigarettes per day in the STOMP Consortium (P-value <5 × 10⁻⁷; David et al. ¹⁸) included in the Detroit Neighborhood Health Study Genetic Risk Score (n=399).

SNP	Chromosome	BP position	Nearby genes	Alleles	Coded AF	Effect size
rs2036527	15	76638670	CHRNA5	A/G	0.22	0.040
rs667282a	15	76650527	CHRNA5	C/T	0.29	0.033
rs3101457	1	242599837	C1orf100	A/G	0.75	0.041
rs938682	15	76683602	CHRNA3	A/G	0.71	0.033
rs547843	15	23975140	LOC503519	C/G	0.65	−0.035
rs3813570a	15	76619887	PSMA4	C/T	0.26	0.033

Abbreviations: AF, allele frequency; BP, base pair position; CHRNA5=cholinergic receptor, nicotinic, alpha 5; C1orf100=uncharacterized chromosome 1 open reading frame; CHRNA3=cholinergic receptor, nicotinic, alpha 3; LOC503519=uncharacterized; PSMA4=proteasome (prosome, macropain) subunit, alpha type 4; SNP, single-nucleotide polymorphism.

Note: When the original STOMP (David et al.¹⁸) SNP was not available for analysis in the DNHS, a proxy SNP (r²>0.9) was used in its place; rs667282 served as a proxy for rs667282 (r²=0.924), rs7163730 served as a proxy for rs3813570 (r²=0.916).

Table 2. Top genetic variants associated with cigarettes per day in the STOMP Consortium (P-value <5 × 10−7; David et al. 18) included in the Detroit Neighborhood Health Study Genetic Risk Score (n=399).

Table 2. Top genetic variants associated with cigarettes per day in the STOMP Consortium (P-value <5 × 10⁻⁷; David et al. ¹⁸) included in the Detroit Neighborhood Health Study Genetic Risk Score (n=399).