Table 3.

Adverse events

Adverse events	Grade 1 or 2	Grade 3 or 4
Hand-foot syndrome	8 (23%)	12 (34%)
Fatigue	17 (49%)	6 (17%)
Rash	13 (37%)	4 (11%)
Emesis	10 (29%)	4 (11%)
Hypertension	7 (20%)	4 (11%)
Nausea	18 (51%)	3 (9%)
Arthralgias	6 (17%)	3 (9%)
Diarrhea	20 (57%)	2 (6%)
Dehydration	1 (3%)	2 (6%)
Infection	1 (3%)	2 (6%)
Anorexia	10 (29%)	1 (3%)
Headache	8 (23%)	1 (3%)
Mucositis	7 (20%)	1 (3%)
Elevated liver function tests	6 (17%)	1 (3%)
Rigors/chills	4 (11%)	1 (3%)
Joint function	3 (9%)	1 (3%)
Neutropenia	2 (6%)	1 (3%)
Dyspnea	2 (6%)	1 (3%)
Acne	1 (3%)	1 (3%)
Hypotension	1 (3%)	1 (3%)
Hypophosphatemia	0	1 (3%)
Thrombosis	0	1 (3%)
Urticaria	0	1 (3%)
Pleural effusion	0	1 (3%)
Alopecia	18 (51%)	0
Pain—other	17 (48%)	0
Constipation	10 (29%)	0
Pruritus/itching	10 (29%)	0
Sensory neuropathy	9 (26%)	0
Weight loss	9 (26%)	0