Table 1.
Mice | bearing | Treatment | Dose (mg/kg) | AUC (μg·h/g tissue) | Ref. | |
---|---|---|---|---|---|---|
plasma | tumor | |||||
Female C3Hf/Kam | Murine ovarian Oca-1 carcinoma | PG-PTX | 20 | 184.1 | 1097.3 | [23] |
Paclitaxel | 20 | 1.8 | 211.4 | |||
PG-PZX/Paclitaxel ratio | 100.9 | 5.2 | ||||
Female nude | Human H460 lung cancer | PGG-PTX | 40 | 3454.4 | 2496 | [21] |
Paclitaxel | 40 | 146.3 | 322.5 | |||
PG-PTX/Paclitaxel ratio | 23.6 | 7.7 |