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. 2010 Dec 23;3(1):17–42. doi: 10.3390/cancers3010017

Table 3.

In vitro evaluations of polymeric-paclitaxel micelles and Taxol in various cancer cell lines.

Cancer Drug Genexol-PM Taxol NK-105 Taxol NK-105 Taxol
IC70 (μg/mL) IC50 (μM) IC50 (μM)
Tumor cell line (96 h drug exposure) (48 h drug exposure) (72 h drug exposure)
Eesophageal TE-1 >1.0 >1.0 0.01 0.02
TE-8 0.02 0.02 0.01 0.01
Lung PC-14 0.01 0.01 0.01 0.01
PC-14/TXT 0.15 0.09 0.08 0.06
H460 0.03 0.01
Breast MCF-7 0.002 0.002 >1.0 >1.0 0.01 0.01
Stomach MKN-28 0.03 0.03 0.01 0.21
MKN-45 0.02 0.07 0.01 0.02
Colon DLD-1 0.95 0.26 0.29 0.20
HT-29 0.01 0.01 0.01 0.01
HCT116 0.03 0.01
Ovarian MCAS 0.01 0.01 0.01 0.01
OVCAR-3 0.002 0.004 >1.0 >1.0 >1.0 >1.0
Pancreatic AsPC-1 0.02 0.02
PAN-9 0.03 0.02
PAN-3 0.01 0.004
Ref. [25] [24]