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. 2011 Mar 11;3(1):1285–1310. doi: 10.3390/cancers3011285

Figure 1.

Figure 1.

Cellular redox balance control regulatory pathways determining cell viability. Different effectors can lead to redox system oxidations triggering a plethora of cellular responses. If stimulation does not compromise cell resistance mechanisms negative feed-back systems restore the redox homeostasis and allow cell survival. However, if stimuli cannot be counteracted by the antioxidant machinery, redox status alterations cause irreversible loss of cell viability.