Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Bortezomib inhibits the chymotryptic activity of the proteasome. AML cells were treated with 100 nM bortezomib for 6, 9 or 18 h. Chymotryptic-like (CT), tryptic-like (T) and PGPH-like proteasomal activity was measured as described in the experimental section Proteasome activity is expressed as nmoles substrate (AMC) cleaved per 1 mg cellular protein in one minute ± S.E.M. (A) HL-60; (B) KG-1; (C) Kasumi; (D) OCI AML2; (E) OCI AML3; (F) MOLM13; (G) ML-2; (H) ML-1.
