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Effects of IL-17 and IL-22 on rat skeletal muscle 2-deoxyglucose (2-DG) uptake. Incubation of rat muscle strips with IL-17 or IL-22 inhibits insulin-stimulated increase in glucose uptake in soleus muscle (A), but not in epitroclearis muscle (B). Value for muscle incubated with IL-17 and IL-22 is significantly different than value for muscle incubated with vehicle; *P < .01. Values are mean ± SEM.
