Skip to main content
. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: Biochem J. 2012 Sep 1;446(2):179–190. doi: 10.1042/BJ20112220

Table 1. Summary of Inhibition Values.

Single IC50 or Ki values were obtained from individual experiments from a single batch of oocytes. The values in this table are the mean ± SEM of at least three independent determinations of the inhibition values except where noted.

inhibitor Tracer IC50 or Ki (mM)
PfENT4 adenine [2,8-3H]adenine 0.007 ± 0.002, 3.6 ± 2.0a
[2,8-3H]adenosine 9.0 ± 2.0b
[8-14C]2’-deoxyadenosine 4.4 ± 0.8
adenosine [2,8-3H]adenosine 2.2 ± 1.0
2 ’-deoxyadenosine [8-14C]2’ -deoxyadenosine 1.5 ± 0.1
isopentenyl adenine [8-14C]2’-deoxyadenosine 0.0033 ± 0.0009
trans-zeatin [8-14C]2’-deoxyadenosine 0.020 ± 0.003
cis-zeatin [8-14C]2’-deoxyadenosine 0.190 ± 0.072
PvENT4 adenine [2,8-3H]adenine 0.006 ± 0.002, 3.2 ± 0.5a
[2,8-3H]adenosine 15.0 ± 0.5b
[8-14C]2’-deoxyadenosine 4.9 ± 2.3
adenosine [2,8-3H]adenosine 1.0 ± 0.2
2 ’-deoxyadenosine [8-14C]2’-deoxyadenosine 4.3 ± 0.2
isopentenyl adenine [8-14C]2’-deoxyadenosine 0.0095 ± 0.0028
trans-zeatin [8-14C]2’-deoxyadenosine 0.193 ± 0.021
cis-zeatin [8-14C]2’-deoxyadenosine 0.284 ± 0.069
a

These data were fit to a two-site competition model.

b

These data are the mean from two experiments, and the error is range/2.