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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Free Radic Biol Med. 2013 May 31;63:421–431. doi: 10.1016/j.freeradbiomed.2013.05.036

Figure 4. VEGF and VEGF-B protect against oxidative stress and mitochondrial dysfunction induced by SU1498.

Figure 4

Neurons were cultured in NB for 48 hr in the absence and presence of NAC (5 mM, final 24 hr), VEGF or VEGF-B (100 ng/ml for 48 hr, replenished after 24 hr). After 46 hr of incubation, cells were treated with SU1498 as indicated and labeled with either carboxy-H2DCFCA to detect oxidative stress (green) or TMRE (red) to measure the Δψm as described in “Materials and methods”. Nuclei were counterstained with DAPI. Scale bar: 50 μm. Data are representative of experiments that were repeated at least three times.